Cartoonists have lent their talents to Christmas Seals many times over the years. The most recent I know of is (Green's #2001-T12) Ray Billingsley's Kwanzaa issue of Southeast Florida, American Lung Association. This seal was used in 2001-2 and was the first and only (so far) instance of an ALA Kwanzza seal. Also, this is the only instance of a cartoonist's work being featured on a Christmas Seal. Four designs, self-adhesive, straight die cut. Featuring Billingsley’s comic strip character, “Curtis”.
In 1955 The National Tuberculosis Association had Al Capp create a Li'l Abner Christmas Seal poster.
In 1958 The National Tuberculosis Association had Bela P. Zaboly, aka Bill Zaboly create a Popeye Christmas Seal Advertisement. Illustrated here is an autographed proof.